
Based on what happened next, I ASSUME
it means, "Would you like an enema?"
The Big Bang Theory Season 1, Episode 11

Can I ASSUME that
you've likewise found the experience...?
The Big Bang Theory Season 2, Episode 16

I have no choice but
to ASSUME the worst,
The Big Bang Theory Season 7, Episode 2

And perhaps we've grown so used to horror,
we ASSUME there's no other way.
Game of Thrones Season 5, Episode 1

I ASSUME you mean never again
will you drink all of Penny's beer...
The Big Bang Theory Season 4, Episode 3